Antidepressant  

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-# An agent that [[prevent]]s or [[counteract]]s [[depression]].+'''Antidepressants''' are drugs used for the treatment of [[major depressive disorder]] and other conditions, including [[dysthymia]], [[anxiety disorder]]s, [[obsessive compulsive disorder]], [[eating disorder]]s, [[chronic pain]], [[neuropathic pain]] and, in some cases, [[dysmenorrhoea]], snoring, [[migraine]]s, [[attention-deficit hyperactivity disorder]] (ADHD), [[substance abuse]] and [[sleep disorder]]s. They can be used alone or in combination with other medications.
-An '''antidepressant''' is a [[psychiatric medication]] used for alleviating [[major depressive disorder|major depression]] or [[dysthymia]] ('milder' depression). Drug groups known as [[MAOI]]s, [[tricyclics]], and second-generation antidepressants such as [[SSRI]]s are particularly associated with the term. These medications are now amongst the [[Prescription drug|drugs]] most commonly prescribed by [[psychiatrist]]s and other physicians, and their [[effectiveness]] and [[adverse effects]] are the subject of many studies and competing claims. +The most important classes of antidepressants are the [[selective serotonin reuptake inhibitors]] (SSRIs), [[serotonin–norepinephrine reuptake inhibitors]] (SNRIs), [[tricyclic antidepressants]] (TCAs) and [[monoamine oxidase inhibitors]] (MAOIs). Other drugs used or proposed for the treatment of depression include [[buprenorphine]], low-dose [[antipsychotics]], and [[Hypericum perforatum|St John's wort]].
-Most antidepressants have a delayed onset of action and are usually taken over the course of weeks, months, or sometimes years. They are generally considered distinct from [[stimulants]], and drugs used for an immediate [[happiness|euphoric]] effect only are not generally considered antidepressants. Despite the name, antidepressants are often used in the treatment of other conditions, including [[anxiety disorders]], [[bipolar disorder]], [[obsessive compulsive disorder]], [[eating disorders]], and [[chronic pain]]. Some have also become known as [[lifestyle drug]]s or "mood brighteners".  
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-Other medications that are not usually called antidepressants, including [[antipsychotics]] in low doses and [[benzodiazepines]], may also be used to manage depression, though in the case of "Benzos", there is a serious risk of physical dependence. An extract of the herb [[St John's Wort]] is commonly used as an antidepressant, labeled as a [[dietary supplement]] in some countries. The term ''antidepressant'' is sometimes applied to any therapy (e.g. [[psychotherapy]], [[electro-convulsive therapy]], [[acupuncture]]) or process (e.g. sleep disruption, increased light levels, regular exercise) found to improve clinically depressed mood.  
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-An inert [[placebo]] tends to have a significant antidepressant effect, so establishing something as an antidepressant in a [[clinical trial]] involves demonstrating a significant additional effect. 
==See also== ==See also==
-*[[Antidepressants in Japan]]+* [[Antidepressants in Japan]]
-*[[Depression and natural therapies]]+* [[Atypical depression]]
 +* [[Depression and natural therapies]]
 +* [[Discovery and development of dual serotonin and norepinephrine reuptake inhibitors]]
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Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraines, attention-deficit hyperactivity disorder (ADHD), substance abuse and sleep disorders. They can be used alone or in combination with other medications.

The most important classes of antidepressants are the selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). Other drugs used or proposed for the treatment of depression include buprenorphine, low-dose antipsychotics, and St John's wort.

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Unless indicated otherwise, the text in this article is either based on Wikipedia article "Antidepressant" or another language Wikipedia page thereof used under the terms of the GNU Free Documentation License; or on original research by Jahsonic and friends. See Art and Popular Culture's copyright notice.

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