Behçet's disease
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| - | '''Paroxysmal attacks''' are short, frequent and stereotyped [[symptom]]s that can be observed in various clinical conditions. They are usually associated with [[multiple sclerosis]], [[pertussis]], but they may also be observed in other [[disease|disorder]]s such as [[encephalitis]], head [[Physical trauma|trauma]], [[stroke]], [[asthma]], [[trigeminal neuralgia]], [[breath-holding spells]], [[epilepsy]], [[malaria]], [[tabes dorsalis]], and [[Behçet's disease]]. It has also been noted as a symptom of [[Gratification disorder]] in children. | ||
| - | Paroxysmal attacks in various disorders have been reported extensively and [[ephaptic coupling]] of [[demylinated|myelin]] [[nerves|nerve]] has been presumed as one of the underlying mechanisms of this phenomenon. This is supported by the presence of these attacks in multiple sclerosis and tabes dorsalis, which both involve demyelination of spinal cord neurons. Exercise, tactile stimuli, hot water, anxiety and neck flexion may provoke paroxysmal attacks. Mostly reported paroxysmal attacks are painful tonic [[spasm]]s, [[dysarthria]] and [[ataxia]], [[numbness]] and [[hemiparesis]]. They are typically different from other [[wikt:transience|transient]] symptoms by their brevity (lasting no more than 2 minutes), frequency (from 1-2 times/day up to a few hundred times/day), stereotyped fashion and excellent response to drugs (usually [[carbamazepine]]). Withdrawal of symptoms without any residual [[neurological finding]] is another key feature in their recognition. | + | '''Behçet's disease''', sometimes called '''Behçet's syndrome''', '''Morbus Behçet''', or '''Silk Road disease''', is a rare immune-mediated [[Systemic disease|systemic]] [[vasculitis]] that often presents with mucous membrane ulceration and ocular involvements. Behçet's disease (BD) was named in 1937 after the Turkish dermatologist Hulusi Behçet, who first described the triple-symptom complex of recurrent oral aphthous ulcers, genital ulcers, and [[uveitis]]. As a systemic disease, it can also involve [[visceral organs]] such as the gastrointestinal tract, pulmonary, musculoskeletal, and neurological systems. This syndrome can be fatal, due to ruptured vascular [[aneurysms]], or severe neurological complications. |
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| - | The word [[wikt:paroxysm|paroxysm]] means "sudden attack, outburst", and comes from the [[Greek language|Greek]] παροξυσμός (''paroxusmos''), "irritation, exasperation". | + | |
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| - | ==See also== | + | |
| - | * [[Convulsion]] | + | |
| - | *[[Relapse]] or [[remission (medicine)|remission]], where symptoms become worse or better | + | |
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Behçet's disease, sometimes called Behçet's syndrome, Morbus Behçet, or Silk Road disease, is a rare immune-mediated systemic vasculitis that often presents with mucous membrane ulceration and ocular involvements. Behçet's disease (BD) was named in 1937 after the Turkish dermatologist Hulusi Behçet, who first described the triple-symptom complex of recurrent oral aphthous ulcers, genital ulcers, and uveitis. As a systemic disease, it can also involve visceral organs such as the gastrointestinal tract, pulmonary, musculoskeletal, and neurological systems. This syndrome can be fatal, due to ruptured vascular aneurysms, or severe neurological complications.
Unless indicated otherwise, the text in this article is either based on Wikipedia article "Behçet's disease" or another language Wikipedia page thereof used under the terms of the GNU Free Documentation License; or on research by Jahsonic and friends. See Art and Popular Culture's copyright notice.
