Genotype
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+ | The genotype is the trait that can not be seen. The '''genotype''' is the [[Genetics|genetic]] constitution of a cell, an organism, or an individual (i.e. the specific [[allele]] makeup of the individual) usually with reference to a specific character under consideration. For instance, the human albino gene has two allelic forms, dominant A and recessive a, and there are three possible genotypes- AA (homozygous dominant), Aa (heterozygous), and aa (homozygous recessive). | ||
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+ | It is a generally accepted theory that inherited genotype, transmitted [[epigenetic]] factors, and non-[[hereditary]] environmental variation contribute to the [[phenotype]] of an individual. | ||
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+ | Non-hereditary [[DNA]] mutations are not classically understood as representing the individual's genotype. Hence, scientists and [[physicians]] sometimes talk for example about the (geno)type of a particular [[cancer]], that is the genotype of the disease as distinct from the diseased. | ||
- | Pain may be experienced differently depending on [[genotype]]; as an example individuals with red hair may be more susceptible to pain caused by heat, but [[redheads]] with a non-functional [[melanocortin 1 receptor|melanocortin 1 receptor (MC1R)]] gene are less sensitive to pain from [[electric shock]]. | ||
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The genotype is the trait that can not be seen. The genotype is the genetic constitution of a cell, an organism, or an individual (i.e. the specific allele makeup of the individual) usually with reference to a specific character under consideration. For instance, the human albino gene has two allelic forms, dominant A and recessive a, and there are three possible genotypes- AA (homozygous dominant), Aa (heterozygous), and aa (homozygous recessive).
It is a generally accepted theory that inherited genotype, transmitted epigenetic factors, and non-hereditary environmental variation contribute to the phenotype of an individual.
Non-hereditary DNA mutations are not classically understood as representing the individual's genotype. Hence, scientists and physicians sometimes talk for example about the (geno)type of a particular cancer, that is the genotype of the disease as distinct from the diseased.