List of psychedelic drugs
From The Art and Popular Culture Encyclopedia
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The following is a list of psychedelic drugs of various classes. Serotonergic psychedelics are usually considered to be the classical psychedelics, whereby the other classes are often only considered to have secondary psychedelic properties. Some of these compounds may be classified differently or under several categories, due to unique structural classification, multiple mechanisms of action, or to the fact that the precise pharmacodynamic actions of psychedelic drugs are not yet completely understood. Also, due to the vast amount of possible substitutions and analogs of psychedelic compounds, their total number is quite large and is not fully reflected within this list, leaving room for many that have not yet been sufficiently investigated and even others that have not yet been discovered.
Entries marked with a '#' are naturally occurring compounds.
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Serotonergic psychedelics (serotonin 5-HT2A receptor agonists)
- Indoles
- Tryptamines [more specifically: alkylated tryptamines]
- Dimethyltryptamine (DMT) #, psychoactive ingredient in the Amerindian brew ayahuasca; endogenously present in various plants and animals, including humans, possibly a trace amine neurotransmitter
- 5-MeO-DMT #
- Psilocybin (4-PO-DMT) #, found in the psilocybe genus of mushrooms, a pro-drug, has to be dephosphorylated to psilocin to become psychoactive
- O-Acetylpsilocin (4-AcO-DMT)
- Psilocin (4-HO-DMT) #, found in the psilocybe genus of mushrooms
- Miprocin (4-HO-MiPT) #
- Bufotenin (5-HO-DMT) #, found in the skin and venom of psychoactive toads, its psychedelic activity is disputed
- α-methyltryptamine (αMT/AMT), also has entactogenic properties
- 5-MeO-AMT
- Diethyltryptamine (DET)
- 4-HO-MET
- 4-HO-DET
- Dipropyltryptamine (DPT)
- Diisopropyltryptamine (DiPT)
- 4-HO-DiPT
- 5-MeO-DiPT
- Ergolines [more specifically: Lysergamides] (can be classified as complex tryptamines, also contain a phenethylamine backbone)
- LSD, also known as 'acid'
- Ergine (LSA) #, found in morning glory and Hawaiian baby woodrose seeds
- Ergonovine #
- Ibogoids (can be classified as complex tryptamines)
- Voacangine
- Ibogaine #, also has dissociative properties
- Tryptamines [more specifically: alkylated tryptamines]
- Phenethylamines [more specifically: alkoxylated phenethylamines]
- Substituted phenethylamines
- Substituted amphetamines (alpha-methyl-phenethylamines)
- 2,5-Dimethoxy, 4-substituted amphetamines (DOx)
- Trimethoxyamphetamines (TMA)
- Tetramethoxyamphetamine
- Br-DragonFLY
- NBOMe deriatives
Empathogens/entactogens (serotonin (5-HT) releasing agents)
- Substituted methylenedioxy-phenethylamines (MDxx)
- Alpha-substituted (-alkylated) tryptamines
Dissociatives (NMDA receptor antagonists)
Cannabinoids (CB-1 cannabinoid receptor agonists)
- THC #, the primary active constituent of cannabis (marijuana)
- CBD #, another major active constituent of cannabis, note: unlike THC, does not bind CB1 receptors
- CBN #
- Nabilone, a prescription cannabinoid drug used for nausea and other indications
- Synthetic cannabinoids
Other
- Harmaline #, harmala alkaloids #, and other beta-carbolines, found in ayahuasca, powerful MAOIs (can be classified as indoles)
- Salvinorin A #, an opioid (κ-opioid receptor agonist), found in salvia divinorum sage
- Piperazines, such as pFPP and TFMPP, usually classified as stimulants
- Myristicin # and Elemicin #, found in nutmeg
- Cryogenine (Vertine) #, the active constituent of heimia species
- Atropine #, Scopolamine #, and Hyoscyamine #, from certain solanaceae species
- Ibotenic acid # and Muscimol #, found in Amanita muscaria mushrooms
- Diphenhydramine and its salt Dimenhydrinate
See also
