Senescence
From The Art and Popular Culture Encyclopedia
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Senescence or biological aging is the change in the biology of an organism as it ages after its maturity. Such changes range from those affecting its cells and their function to those affecting the whole organism. There are a number of theories as to why senescence occurs; for example, some posit it is programmed by gene expression changes, others that it is the cumulative damage caused by biological processes. Senescence is not the inevitable fate of all organisms. A variety of organisms, including some cold-blooded animals, have negligible senescence. Whether senescence as a biological process can be slowed down, halted or even reversed, is a subject of current scientific speculation and research.
The word senescence is derived from the Latin word senex, meaning old man, old age, or advanced in age.
See also
- Accelerated aging diseases (DNA repair-deficiency disorders)
- Advanced adult
- Ageing
- Ageing brain
- Calorie restriction
- DNA damage theory of aging
- Evolution of ageing
- Fisher's reproductive value
- Immortality
- Life extension
- List of life extension-related topics
- Maximum life span
- Mitohormesis
- Plant senescence
- Progeria, a disease in which symptoms resembling aspects of aging are manifested in childhood
- Reliability theory of aging and longevity
- SAGE KE
- Strategies for Engineered Negligible Senescence (SENS)
- Sub-lethal damage
- Telomere
- Stem cell theory of aging