A Study in Cocaine: Sherlock Holmes and Sigmund Freud  

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"A Study in Cocaine: Sherlock Holmes and Sigmund Freud" (1968) is a paper by David F. Musto.

"David Musto's "Sherlock Holmes and Sigmund Freud" focuses on the cocaine connection in the early careers of two brilliant investigators." --Cocaine Papers
"Cocaine stimulated the early careers of two brilliant investigators, Sigmund Freud and Sherlock Holmes. In fact, their common attraction to the euphoric properties of the coca leaf may be more than a coincidence. But whatever the Freud-Holmes relationship, the cocaine episodes in each of their lives reflect the impact of a new psychic drug on literature and science. Some of their admirers may deny or overlook this aspect of their careers, thinking that any association with such a drug can only be an embarrassment. But the international enthusiasm for cocaine which antedated and extended beyond their periods of endorsement makes it unlikely that any fair-minded person will censure them." [1]
"As the late Sir Arthur Conan Doyle wrote in The Yellow-Face, which appears in The Memoirs of Sherlock Holmes published by Penguin Books, "[s]ave for the occasional use of cocaine he [Holmes] had no vices, and he only turned to the drug as a protest against the monotony of existence when cases were scanty and the papers uninteresting." This passage provides a backdrop for this lawsuit."[2]

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