Varenicline
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| - | [[Image:Skull with a Cigarette (1886) - Vincent van Gogh.jpg|thumb|right|200px| | + | {{Template}} |
| - | ''[[Skull with a Cigarette]]'' ([[1886]]) - [[Vincent van Gogh]] ]] | + | |
| - | {{Template}}Leaves of certain varieties of the [[plant]] cultivated and harvested to make [[cigarette]]s, [[cigar]]s, [[snuff]], for smoking in [[pipe]]s or for [[chew]]ing. | + | '''Varenicline''' (trade name '''Chantix''' and '''Champix''') is a prescription medication used to treat [[tobacco use disorder]]. It both reduces craving for and decreases the pleasurable effects of [[nicotine]] from [[cigarette]]s and other [[tobacco]] products. |
| - | ==See also== | + | |
| - | *[[Varenicline]] | + | It is a high-affinity [[partial agonist]] for the α4β2 [[nicotinic acetylcholine receptor]] subtype (nACh) that leads to the release of the [[neurotransmitter]] [[dopamine]] in the [[nucleus accumbens]] reward center of the brain when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by [[smoking cessation]]. |
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Varenicline (trade name Chantix and Champix) is a prescription medication used to treat tobacco use disorder. It both reduces craving for and decreases the pleasurable effects of nicotine from cigarettes and other tobacco products.
It is a high-affinity partial agonist for the α4β2 nicotinic acetylcholine receptor subtype (nACh) that leads to the release of the neurotransmitter dopamine in the nucleus accumbens reward center of the brain when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation.
Unless indicated otherwise, the text in this article is either based on Wikipedia article "Varenicline" or another language Wikipedia page thereof used under the terms of the GNU Free Documentation License; or on research by Jahsonic and friends. See Art and Popular Culture's copyright notice.
